(Reuters Health) - Infertile men may have an increased risk of developing aggressive prostate cancer, researchers reported on Monday in what could be an important move toward identifying those who will benefit from screening for the disease.
Prostate cancer is one of the most common cancers in men, affecting about 160 per 100,000 every year and killing 26. While doctors can screen for it, many prefer not to do so because most tumors grow slowly and never cause any harm.
The researchers tracked more than 22,000 Californian men who had been evaluated for infertility between 1967 and 1998.(Read entire article)
Researchers have found that infertile men who did develop prostate cancer were more than two-and-a-half times more likely to develop high-grade or aggressive prostate cancers, which are more likely to grow and spread quickly, than fertile men.
"These results, if confirmed, also suggest that men
identified with male factor infertility earlier in life may be considered for
prostate cancer screening, given the elevated risk specifically for high-grade
disease," write researcher Thomas J. Walsh, MD, of the University of Washington School of Medicine in