2008-09-01 Kids with older dads at higher bipolar risk: study

http://www.reuters.com/article/2008/09/01/us-bipolar-fathers-idUSL138021820080901

(Reuters) - Children born to fathers older than 30 are more likely to develop bipolar disorder, a common condition sometimes known as manic depression, researchers reported on Monday.

The paternal risk also grows with the age of a father, rising to 37 percent by the time a man is 55 years, said Emma Frans, an epidemiologist at the Karolinska Institute in Sweden, who led the study.

 The brain disorder causes extreme shifts in mood, energy and ability to function. It is marked by high periods of elation or irritability and low periods of sadness and hopelessness that can last months.(Read entire article)

2008-09-01 Children of older dads face higher bipolar risk - Older sperm may have mutations, but risk is still small, study authors say

http://www.msnbc.msn.com/id/26497981/

Children born to older fathers face a greater chance of developing bipolar disorder, according to one of the largest studies linking mental illness with advanced paternal age.

Previous research has connected schizophrenia and autism with older dads, and a Danish study published last year added bipolar disorder to the list. The new study led by researchers at Sweden's Karolinska Institute strengthens the evidence.

The leading theory is that older men's sperm may be more likely to develop mutations. Even so, the odds of a person becoming bipolar are so low that the study's authors said it shouldn't dissuade older men from becoming fathers. (Read entire article)