2008-01-11 Arthritis drug may ease dementia: case-report


(Reuters Health) - In a new report, U.S. researchers describe the improvement in brain function that occurred in a patient with Alzheimer's disease just minutes after receiving an injection in the spine of the arthritis drug Enbrel (also known as etanercept).

For instance, just prior to treatment the patient was agitated and could not name the state. Ten minutes after treatment, he appeared calmer, more attentive, less frustrated and was able to correctly name the state. Further improvements in mental functioning, memory, and other cognitive parameters were noted at 2 hours.(Read entire article)

2008-01-15 Study: Arthritis Drug Shows Promise in Reversing Symptoms of Alzheimer's


A patient with Alzheimer's disease had their condition improve hugely just minutes after receiving a special injection of a prescription drug approved to treat psoriasis and rheumatoid arthritis and other conditions, according to a new study.

The drug, co-marketed in the U.S. by Amgen and Wyeth under the name Enbrel, dramatically reversed symptoms of an Alzheimer’s disease sufferer minutes after it was injected into the patient's spine, researchers in the U.S. discovered. The drug, sold in Australia as Etanercept, has also been used off-label for treating Alzheimer's.

A report on the new study appeared in the Journal of Neuroinflammation this week.(Read entire article)