Women in a 30-year follow-up study who had ovaries surgically removed before menopause had nearly double the risk for developing age-related dementia later in life. But the increased risk was not seen in women who had both ovaries removed and were also treated with estrogen until at least age 50.
The study, published in the latest online issue of the journal Neurology, suggests there is a "critical age window" for the protective effect of estrogen on women's brains, says researcher Walter A Rocca, MD, MPH, of the Mayo Clinic in Rochester, Minn.(Read entire article)
Women who have their ovaries removed before menopause run a heightened risk of developing dementia or other mental problems later in life — unless they take estrogen until age 50, a new study suggests.
Experts said the research needs to be confirmed by further study, but the findings suggest another issue for premenopausal women and their doctors to discuss as they consider ovary removal.
And if they decide to go ahead with surgery, they need to consider the risks and benefits of taking estrogen to age 50, said Dr. Walter Rocca, a Mayo Clinic neurologist and lead study author. (Read entire article)