2007-01-15 New Clue to Late Stage Alzheimer's Cause Found



A major international study has found that a gene known as SORL1 may provide yet another clue into the cause of late onset Alzheimer's disease.

The research, which was supported in part by the U.S. government's National Institutes of Health, examined blood samples from 6,000 people from a number of different racial, ethnic, and national backgrounds for signs of Alzheimer's disease.

Alzheimer's is caused by plaque forming in the brain to impede cognitive functioning, especially in older people. Eventually, total dementia, including memory loss and impairment of daily functioning, occurs in Alzheimer's patients. So far, no cure has been found.(Read entire article)


2007-01-14 Study Links Gene to Alzheimer's Disease


A huge international study has identified a gene that apparently can raise the risk of developing the most common form of Alzheimer's disease, a discovery that may help scientists develop new treatments.

Scientists analyzed DNA from more than 6,000 people from a variety of ethnic groups and found evidence implicating certain versions of the gene, called SORL1.

It is too soon to tell how much those gene versions raise the risk of getting Alzheimer's, or what percentage of cases they account for, the researchers said. They said the effect on risk appears to be modest.(Read entire article)